Generation of AAVS1 and CLYBL STRAIGHT-IN v2 acceptor human iPSC lines for integrating DNA payloads. Blanch-asensio, A., Vaart, B. Van Der, Vinagre, M., Groen, E., Arendzen, C., Freund, C., Geijsen, N., Mummery, C. L., & Davis, R. P. (2023). Stem Cell Research, 66(November 2022), 102991.
X. Fan, M. Bialecka, I. Moustakas, E. Lam, V. Torrens-Juaneda, N. V. Borggreven, L. Trouw, L. A. Louwe, G. S. K. Pilgram, H. Mei, L. van der Westerlaken and S. M. Chuva de Sousa Lopes: Single-cell reconstruction of follicular remodeling in the human adult ovary. Nature Communications (2019)
Jasin Taelman, Sylwia M. Czukiewska, Ioannis Moustakas, Yolanda W. Chang, Sanne Hillenius, Talia van der Helm, Lotte E. van der Meeren, Hailiang Mei, Xueying Fan and Susana M. Chuva de Sousa Lopes: Characterization of the human fetal gonad and reproductive tract by single-cell transcriptomics. Developmental Cell (2024)
Arend W. Overeem, Yolanda W. Chang, Ioannis Moustakas, Celine M. Roelse, Sanne Hillenius, Talia Van Der Helm, Valérie F. Van Der Schrier, Manuel A.F.V. Gonçalves, Hailiang Mei, Christian Freund and Susana M. Chuva de Sousa Lopes: Efficient and scalable generation of primordial germ cells in 2D culture using basement membrane extract overlay. Cell Reports Methods (2023)
Developments in medical technology can raise moral dilemmas. This also applies to stem cell research and specifically to the development of embryo models. Ethical, legal and social issues (ELSI), also known as Socially Responsible Innovation (MVI), are therefore a strong point of attention within the program.
The Dutch Embryo Model Meeting presents a valuable opportunity for scientists involved in research with stem-cell-based embryo models to showcase their work, and many of the researchers involved in our program eagerly anticipate presenting their research findings at this event.
The recent report of the Rathenau Institute, entitled 'Seeds for a Societal Debate', is now online!
In the Netherlands, about two thousand people live with the muscle disease FSHD. With this condition, the muscles increasingly lose strength, which can ultimately cause people to end up in a wheelchair.
